6 Best Restaurants in San Diego, California

Breakfast Republic

$ | Ocean Beach

Creeping toward 20 locations, this breakfast chain is spreading like wildfire thanks to the owner, Johan Engman’s obsession with the first meal for the day. Served out of an Airstream kitchen, hot breakfast plates hit your table within 20 minutes and nearly every dish puts a spin on a standard like the tres leches vegan pancakes, the gouda shrimp and grits, and the breakfast burrito with Jurassic pork. No one leaves hungry, or unhappy for that matter, especially with drinks like the lychee mimosa and the house-made bloody Marys. The warehouse-style decor and dog-friendly patio meld perfectly with the Ocean Beach vibe.

Las Cuatros Milpas

$
One of the oldest restaurants in San Diego, having opened in 1933, Las Cuatros Milpas feels like a closely held secret in Barrio Logan. Open daily until 3 pm, it almost inevitably attracts a big lunchtime rush, though the wait is worth it for the homemade tortillas, beans with chorizo, and rolled tacos. The menu is simple, though everything is delicious, and the interior—with checkered picnic tables—looks like it hasn't changed in 85 years.

Mrkt Space

$ | La Jolla

A popular meeting place for casual connections and grab-and-go goodness, this café–bar–market is a great place to start your day with an energy boost like avocado egg cups on toasted sourdough or smoked salmon toast with jalapeño and micro greens. Later in the day, place your order at the counter for “not an ordinary sandwich” like the prosciutto with stracciatella and pesto, afternoon nibbles like smoothies and charcuterie boards, or cocktails and wines by the glass. If you’ve ever grabbed a bite at a café and wished you could replicate it at home with signature ingredients, the market portion of this space will make you very happy.

Recommended Fodor's Video

Panama 66

$ | Balboa Park

Adding a dose of hip to Balboa Park, this gastropub, located adjacent to the San Diego Museum of Art's sculpture garden, offers a stylish pit stop pretheater or between museum-hopping. The menu features grab-and-go options as well as dine-in upscale pub fare with several vegan options and a weekend brunch.

Panama 66 does not take reservations.

1450 El Prado, San Diego, California, 92101, USA
619-696–1966
Known For
  • varied menu including selection of shareable boards and plates
  • live music most nights
  • local San Diego brews
Restaurants Details
Rate Includes: No dinner Mon. and Tues. Labor Day–Memorial Day

Sandpiper Wood Fired Grill & Oysters

$$ | La Jolla

As the sister restaurant of La Jolla’s Georges at the Cove, this laid-back restaurant is the perfect spot to chill with friends after a day in the sand and share oysters from the raw bar or rosemary Parmesan fries dipped in jalapeño ranch. Grab a seat on the dog-friendly patio or head indoors for grilled favorites including octopus, prime rib, and cast-iron focaccia with honey ricotta. A smoky element takes flavors up a notch, with nearly every dish touching the wood-fired grill. Rounding out the menu are house-made pastas and desserts prepared by Aly Lyng, the pastry chef at George’s at the Cove. Sunday brunch and happy hour (4–5:30 pm) are both on point, especially with tempting offers that include a dozen oysters on the house with any purchase of a bottle of Champagne.

Trilogy Sanctuary

$ | La Jolla

Perched on a rooftop in La Jolla, this café features a mindful menu of bowls, tacos, and other creative entrées that are all 100% organic, vegan, gluten-free, dairy-free, and soy-free. There's also a boutique with sustainable products and a yoga studio with aerial yoga, sound healing, and training workshops.