Fodor's Expert Review Acquerello

At this true San Francisco dining gem, chef and co-owner Suzette Gresham has elicited plenty of swoons over the years with high-end but soulful Italian cooking that is worth every penny. Her cuttlefish "tagliatelle" is a star of the menu, which features both classic and cutting-edge dishes. Dinners are prix fixe, with three, four, or five courses and at least four choices within each course. Co-owner Giancarlo Paterlini oversees the service, and his son Gianpaolo presides over the roughly 2,000-bottle list of Italian wines. The room, in a former chapel, with a vaulted ceiling and terra-cotta and pale-ocher palette, is refined but never stuffy.